Molecular Basis of Fanconi Anemia
Molecular basis of the diseaseFanconi anemia affects DNA repair enzymes, which predisposes affected individuals to cancer. The genes involved in this condition code for proteins involved in the recognition and repair of DNA and mutations in these genes means cells continue to live even though they contain damaged DNA.Feb 26, 2019
What is the cause of Fanconi Anaemia?
What is the DNA repair defect underlying Fanconi anemia?
What type of anemia is Fanconi anemia?
Where is the Philadelphia chromosome found?
Which congenital upper extremity deformity is associated with Fanconi anemia?
What percentage of the population has Fanconi anemia?
What is the FA pathway?
What is RBC aplasia?
How is DNA replication or repair affected Fanconi anemia?
What are the symptoms of Fanconi anemia?
- Bone marrow related symptoms. These may include tiredness or fatigue, frequent infections, and bleeding problems.
- Physical abnormalities. These may involve the skin, bones, kidneys, gastrointestinal system, brain, spinal cord, eyes, ears, and the reproductive systems.
Is Fanconi syndrome fatal?
develops, leading to progressive renal failure that may be fatal before adolescence.
What does Fanconi anemia do?
When is Fanconi anemia diagnosed?
Is Fanconi anemia Megaloblastic?
What triggers the Philadelphia chromosome?
Why is it called Philadelphia chromosome?
How does the Philadelphia chromosome activate an oncogene?
What is Amelia and Phocomelia?
What is radial ray deficiency?
What is Meromelia birth defect?
How many people are carriers for Fanconi anemia?
Who discovered Fanconi anemia?
Can Fanconi anemia be acquired?
What is the primary role of the Fanconi Anaemia proteins in the pathways that repair DNA interstrand crosslinks?
What is the FA core complex?
What is EPO used for?
How is pure red cell aplasia diagnosis?
What drugs cause red cell aplasia?
How many FA genes are there?
Which type of anemia is caused by a vitamin b12 deficiency?
It is needed to absorb vitamin B12. This type of B12 deficiency anemia is called pernicious anemia.
What is myelofibrosis?
Why does Fanconi cause acidosis?
What is Type 2 RTA?
Which drugs cause Fanconi syndrome?
Is aplastic anemia the same as Fanconi anemia?
What is Evans syndrome?
Who treats Fanconi anemia?
How does Fanconi anemia develop?
How is Fanconi Anaemia diagnosed?
Is Fanconi anemia monogenic?
What is Fanconi anemia pathway?
What is the pathophysiology of Fanconi anemia?
Why is it called paroxysmal nocturnal hemoglobinuria?
Does the Philadelphia chromosome run in families?
What does reciprocal translocation cause?
Which leukemia is associated with Philadelphia chromosome?
What is P210 BCR abl1?
How does Gleevec work at the molecular level?
Is aneuploidy a trisomy?
What type of mutation occurs in the Philadelphia chromosome?
Is Philadelphia chromosome reciprocal translocation?
What is Philadelphia chromosome negative?
What causes Peromelia?
What causes seal syndrome?
|Cases of severe thalidomide-induced phocomelia.|