Factor H Autoantibodies
Autoantibodies to Factor H, can block the function of the control protein, allowing for inappropriate activation of the alternative pathway of complement. Factor H Autoantibody has been associated with atypical Hemolytic Uremic Syndrome (aHUS), also known as complement related HUS.
What does factor H do?
What is factor H in immunology?
What is factor H test?
What is atypical hemolytic uremic syndrome AHUS?
What is factor H binding protein?
What is complement deficiency?
What produces factor H?
What do Anaphylatoxins do?
Is Factor HA protein?
What is the main reason for hemolytic uremic syndrome?
Is hemolytic uremic syndrome fatal?
How rare is hemolytic uremic syndrome?
What is activation of complement?
What is fHBP?
What are the four major functions of the complement system?
What disease can cause a low complement level?
What is the most serious complement deficiency?
What causes complement deficiencies?
Acquired deficiency can be caused by infection. MBL deficiency is thought to be the most common. Uncontrolled or deranged complement activity can also cause disease by promoting inflammation. The complement system can be involved in the pathogenesis of autoimmune diseases.