Epidermal Nevus Syndromes

Epidermal Nevus Syndromes

What is the treatment for nevus syndrome?

Therapy is often challenging. Epidermal nevi are usually resistant to topical and intralesional steroids, dithranol, topical retinoids, and cryosurgery. Topical calcipotriol may be effective. In the United States, calcipotriol is not approved for children younger than 12 years.

Can epidermal nevus be inherited?

It is also not inherited from the parental germ cells. In some cases, the somatic mutation in the FGFR3 gene is located within a germ cell of one individual, in which case it becomes heritable. Affected children will show the presence of the mutation within every cell rather than only the cells of the epidermal nevus.

Is epidermal nevus a tumor?

The tumor is usually benign, although rarely cancerous (malignant ) tumors develop. Some affected individuals have only an epidermal nevus and no other abnormalities. However, sometimes people with an epidermal nevus also have problems in other body systems, such as the brain, eyes, or bones.

How do you treat epidermal nevus?

The treatment of choice for small epidermal nevi is surgical excision. Superficial means of removal frequently result in recurrence. Aggressive approaches may be more successful, but also carry a higher risk of postoperative scarring.

Leave a Comment