Diabetes Mellitus Type 1 Pathophysiology
Type 1 DM is the culmination of lymphocytic infiltration and destruction of insulin-secreting beta cells of the islets of Langerhans in the pancreas. As beta-cell mass declines, insulin secretion decreases until the available insulin no longer is adequate to maintain normal blood glucose levels.
What happens in type 1 diabetes mellitus?
What is the pathogenesis of DM type 1 and 2?
What happens to a type 1 diabetes without insulin?
Without insulin, your body will break down its own fat and muscle, resulting in weight loss. This can lead to a serious short-term condition called diabetic ketoacidosis.
Why do type 1 diabetes need insulin?
How is the pathophysiology of type 1 diabetes different from that of type 2 diabetes?
What is the etiology and pathophysiology of diabetes?
What is type 1 diabetes Pubmed?
What are the risk factors for developing type 1 diabetes?
- Family history. Your risk increases if a parent or sibling has type 1 diabetes.
- Environmental factors. Circumstances such as exposure to a viral illness likely play some role in type 1 diabetes.
- The presence of damaging immune system cells (autoantibodies). …